Carlo Maley, Ph.D.

Helen Diller Family Comprehensive Cancer Center
Director of the Center of Evolution and Cancer
University of California San Francisco (UCSF)

Carlo Maley is the director of the Center of Evolution and Cancer at the University of California San Francisco (UCSF) Helen Diller Family Comprehensive Cancer Center. He is also an associate professor in the Surgery Department at UCSF and part of the Seattle Barrett’s Esophagus Research Program. He received a M.Sc. degree from the University of Oxford, studying evolutionary biology with W.D. Hamilton. He earned his Ph.D. in computational biology from MIT, working with Rodney Brooks and Michael Donoghue, and then moved into cancer biology as a postdoc with Stephanie Forrest at the University of New Mexico and as a staff scientist with Brian Reid at the Fred Hutchinson Cancer Research Center. He was an assistant professor at the Wistar Institute for 5 years before moving to UCSF. His research lies at the intersection of evolutionary biology, computational biology and cancer biology and includes both dry lab (computational) and wet lab (genetics of tumors and evolutionary tissue culture experiments) projects. He is interested in how cells evolve in neoplastic progression and in response to therapy with the goal of controlling that evolution to prevent cancer and therapeutic resistance.